Next-Generation Anti-Aging Drawing Out Rejuvenation from Within

At AVAN TOKYO, we have introduced regenerative medicine utilizing stem cell culture supernatant (adipose-derived stem cells), providing treatment that addresses aging itself.
Stem cell culture supernatant contains abundant growth factors, cytokines, exosomes, and other bioactive substances, with expected effects including inflammation suppression, tissue repair, angiogenesis, and cellular activation. This is not merely symptomatic treatment but therapy that awakens the body’s inherent capacity to heal and rejuvenate.
While conventional aesthetic medicine has focused on changing appearance, regenerative medicine aims to rejuvenate at the cellular level. Rather than superficial changes, this approach enhances the body’s regenerative capacity itself, thereby offering the expectation of natural and sustained effects.
At AVAN TOKYO, we offer various administration methods tailored to each patient’s objectives and condition. This represents a treatment option that can address a wide range of needs, from comprehensive rejuvenation to improvement of joint pain, hair loss treatment, and skin rejuvenation.
Infusion Therapy (Intravenous Administration)

Stem Cell Culture Supernatant Infusion Promoting Comprehensive Rejuvenation
Systemic administration of stem cell culture supernatant via intravenous infusion is expected to improve chronic fatigue, regulate immune balance, enhance skin quality, firmness, and luster, suppress inflammation, slow the aging process, and stabilize the autonomic nervous system.
This treatment is selected by those experiencing declined recovery capacity, increased fatigue, and perceptions of aging. For such individuals, it serves as an internal reset therapy for the body. Infusion administration can deliver culture supernatant to cells throughout the body via the bloodstream, thereby offering the expectation of systemic effects that cannot be obtained through localized treatment.
A single session takes approximately 30 to 60 minutes and can be received in a relaxed position in a reclining chair. You can return to daily life immediately after treatment, with virtually no downtime. By accumulating regular treatments, you can experience the effects more fully.
Local Injection into Joints and Soft Tissues

Stem Cell Culture Supernatant “Joint Injection” for Osteoarthritis and Joint Pain
Direct injection of culture supernatant into the knee joint is expected to calm inflammation, promote repair of cartilage-surrounding tissues, and reduce pain.
We propose this as regenerative medicine targeting fundamental improvement for concerns such as difficulty with stair climbing, inability to sit in seiza position, and pain during ambulation. This option is gaining attention as a low-burden alternative for the body, particularly for those who have not experienced improvement with hyaluronic acid injections or wish to avoid surgical intervention when possible.
Joint injections accommodate not only the knee joint but also the shoulder joint, elbow joint, ankle, and other areas. We will propose an optimal treatment plan according to joint condition and patient concerns. Treatment time is approximately 10 to 20 minutes, with minimal impact on daily life.
Local Administration to Scalp and Hair (Subcutaneous Injection)

Stem Cell Culture Supernatant “Hair Growth Injection” for Thinning Hair and Hair Loss
Direct injection of culture supernatant into the scalp is expected to activate hair matrix cells, improve blood flow around hair follicles, and maintain anagen-phase hair.
The primary characteristic of this treatment is that, unlike pharmacological therapy, it establishes a regenerative environment for the hair follicles themselves. This treatment is suitable for those concerned about medication side effects, individuals wishing to initiate early hair loss prevention measures, and those aiming for natural hair regrowth.
Scalp injections accommodate not only male pattern hair loss but also female pattern hair loss and diffuse alopecia. We adjust injection volume and treatment frequency according to scalp condition and degree of hair loss progression. Treatment time is approximately 30 to 40 minutes, and we are committed to careful treatment that minimizes discomfort.
Local Administration and Delivery to Skin (Face, Neck, Dorsal Hands, etc.)

Stem Cell Culture Supernatant “Skin Rejuvenation” for Skin Firmness, Fine Lines, and Pores
Direct injection or delivery to the skin of the face, neck, dorsal hands, and other areas is expected to improve skin firmness and elasticity, reduce fine lines, tighten pores, improve dullness, and achieve skin rejuvenation at the tissue level.
Unlike treatments such as hyaluronic acid that physically augment volume, this approach enhances the skin’s regenerative capacity itself, thereby enabling pursuit of natural and sustained rejuvenation. This treatment is suitable for those wishing to improve skin quality from its foundation and those seeking natural rejuvenation.
Administration methods include direct injection and delivery using devices such as electroporation. We will propose the most appropriate method according to your skin condition and preferences. Treatment time is approximately 30 to 50 minutes, and you may apply makeup before leaving.
Intranasal Administration

Intranasal Administration Approaching the Entire Body Through Nasal Mucosa
Administration of stem cell culture supernatant intranasally allows direct absorption through nasal mucosa, with expected benefits to the brain and nervous system.
Intranasal administration is a suitable method for those uncomfortable with injections or those wishing to incorporate regenerative medicine more conveniently. Because nasal mucosa is rich in blood vessels with high absorption rates, systemic effects comparable to infusion are expected. Additionally, because this represents administration from a site proximate to the brain, effects on the nervous system are also attracting attention.
The procedure is extremely simple, involving only spraying into the nasal cavity like a nasal medication. There is no pain, and completion occurs within minutes. With regular use, benefits are expected including fatigue reduction, sleep quality improvement, and concentration enhancement.
Topical Application and External Use

Culture Supernatant-Containing Products for Home Care
You may use serums and creams containing stem cell culture supernatant as home care at your residence.
External products can enhance effectiveness when used in combination with clinic treatments. They are also effective as maintenance to sustain the effects of clinic treatments. By incorporating them into daily skincare routines, they continuously support the skin’s regenerative capacity.
Products containing culture supernatant differ from ordinary cosmetics in that they contain active ingredients such as growth factors and exosomes. They improve skin firmness and elasticity, reduce dullness, and lead to skin with refined texture. We will provide detailed explanations regarding usage methods during consultation.
Why Our Clinic Emphasizes Regenerative Medicine
At AVAN TOKYO, we position regenerative medicine as the next stage connecting treatments that reshape form with medicine that rejuvenates at the cellular level.
Surgical treatment and regenerative medicine, dermatological treatment and regenerative medicine, anti-aging and regenerative medicine. Through this integration, we will provide medical care in which not only appearance but the body itself rejuvenates. Fundamentally slowing aging and extending health span—this is the medicine that AVAN TOKYO pursues.
Recommended for Those Who:
- Wish to fundamentally slow aging
- Seek to improve knee pain through non-surgical means when possible
- Desire fundamental measures against thinning hair and hair loss
- Want to rejuvenate skin quality from its foundation
- Wish to enhance not only aesthetic outcomes but also health span
- Experience increased fatigue or declined recovery capacity
- Aim for natural and sustained rejuvenation
Toward an Era of Rejuvenation from Within—A New Choice Called Regenerative Medicine

Regenerative medicine is medical care that once again bestows rejuvenating capacity upon aged tissues. Not merely anti-aging, but medicine that invests in your future health and youthfulness.
Please experience that first step at AVAN TOKYO. We will propose personalized treatment plans tailored to each individual patient and provide maximum support toward realizing your ideals.