Stem Cell Culture Supernatant “Skin Rejuvenation” for Skin Firmness, Fine Lines, and Pores
Treatment Rejuvenating the Skin Itself
AVAN TOKYO’s stem cell culture supernatant dermal administration is treatment that aims to improve skin firmness and elasticity, reduce fine lines, tighten pores, improve dullness, and achieve skin rejuvenation at the tissue level by directly injecting or delivering culture supernatant to the skin of the face, neck, dorsal hands, and other areas. We provide skin regenerative medicine in Ginza.
Unlike treatments such as hyaluronic acid that physically augment volume, this approach enhances the skin’s regenerative capacity itself, thereby offering the expectation of natural and sustained rejuvenation. This treatment is suitable for those wishing to improve skin quality from its foundation and those seeking natural rejuvenation.
What Is Stem Cell Culture Supernatant Dermal Administration?
Stem cell culture supernatant dermal administration includes methods of directly injecting supernatant obtained during the process of culturing adipose-derived stem cells into the skin and methods of delivery using devices such as electroporation. This supernatant contains abundant growth factors, cytokines, exosomes, and other bioactive substances, and skin cell activation and regeneration are expected.
While conventional aesthetic treatments have been limited to superficial improvements, stem cell culture supernatant dermal administration acts upon the dermal layer of the skin and aims for fundamental skin quality improvement by promoting collagen and elastin production.
While hyaluronic acid injection temporarily plumps the skin, stem cell culture supernatant enhances the skin’s regenerative capacity itself, thereby offering the expectation of more natural and sustained effects. Rather than paralyzing facial muscles like botulinum toxin, this is treatment that rejuvenates the skin itself.
Expected Effects
The following effects are expected from stem cell culture supernatant dermal administration:
Improvement of Skin Firmness and Elasticity
Skin firmness and elasticity improve through promotion of collagen and elastin production in the dermal layer. Effects are expected for those concerned about sagging and those experiencing loss of skin elasticity.
Reduction of Fine Lines
Fine lines become less noticeable through improved skin moisture retention capacity and increased collagen. Effects are expected for fine lines around the eyes and mouth.
Pore Tightening
Through enhanced skin regenerative capacity, open pores are tightened and the skin is led toward refined texture. Effects are expected for those concerned about open pores.
Dullness Improvement
Through normalization of skin turnover, old dead skin cells are expelled and the skin is led toward transparency. Skin tone brightens and dullness improves.
Rejuvenation of the Skin Itself
Through skin cell activation, the entire skin rejuvenates. Rejuvenation from within is expected that cannot be obtained through external care alone.
Skin Quality Improvement
Improvement is expected for various skin concerns including dry skin, sensitive skin, and acne scars. The skin barrier function improves and the skin is led toward health.
Recommended for Those Who:
Stem cell culture supernatant dermal administration is suitable for individuals with the following concerns:
Those who have lost skin firmness and elasticity and are concerned about sagging. This is suitable for those concerned about sagging of the cheeks and eye area and blurring of the facial contour.
Those concerned about fine lines and open pores. This is suitable for those wishing to improve fine lines around the eyes and mouth and open pores on the cheeks.
Those concerned about dullness and skin tone. This is suitable for those wishing to recover transparent, bright skin.
Those resistant to hyaluronic acid injection. This is suitable for those wishing to avoid unnatural results and seeking natural rejuvenation.
Those concerned about aging of the neck and dorsal hands. This is suitable for those wishing to perform anti-aging care not only on the face but also on the neck and hands.
Those wishing to fundamentally improve skin quality. This is suitable for those not satisfied with superficial care and wishing to improve skin from its foundation.
Our Clinic’s Commitment
At AVAN TOKYO, we provide stem cell culture supernatant dermal administration treatment with the following commitments:
Use of High-Quality Culture Supernatant
The stem cell culture supernatant used at our clinic is manufactured under rigorous quality control. We adopt only high-quality products that meet all standards including growth factor and exosome content and safety. We are particular about quality for creating beautiful skin.
Selection of Administration Method Tailored to Patient’s Skin Quality
We accommodate both direct administration through injection and delivery using devices, and propose the most appropriate method according to the patient’s skin condition and preferences. We may recommend the delivery method for those sensitive to pain and the injection method for those seeking greater effects.
Treatment Minimizing Pain
In the case of administration through injection, we minimize pain by using ultrafine needles and applying anesthetic cream. Through careful technique, we reduce patient burden.
Continuous Follow-Up and Effect Measurement
After treatment, we periodically confirm progress and record skin condition through photography and other means. We objectively evaluate effects and adjust treatment plans as necessary.
Administration Methods
Stem cell culture supernatant dermal administration primarily includes two methods:
Direct Administration Through Injection
Using ultrafine needles, culture supernatant is directly injected into the dermal layer of the skin. Through water light injection (Dermashine) or hand injection, injection is performed across the entire face or to areas of concern. Because this delivers directly to the dermal layer, high effects are expected.
Delivery Using Devices
Using devices such as electroporation or iontophoresis, culture supernatant is penetrated into the skin. Because needles are not used, pain is minimal and downtime is virtually nonexistent. This is recommended for those sensitive to pain or first-time patients.
Treatment Process
Stem cell culture supernatant dermal administration treatment proceeds according to the following process:
Consultation
We conduct detailed inquiries regarding the patient’s skin concerns, skincare to date, treatment history, and other relevant factors. We examine skin condition and propose the most appropriate treatment method. We provide detailed explanations regarding the mechanism of stem cell culture supernatant dermal administration, expected effects, risks and side effects, costs, and other matters.
Skin Photography (Initial Visit)
To record the pre-treatment state, we photograph the skin. This serves as material for objectively evaluating post-treatment effects.
Treatment Day
Cleansing and Face Washing We remove makeup and perform face washing. Performing the procedure in a clean state is important.
Anesthesia (For Injection) In the case of administration through injection, we apply anesthetic cream to reduce pain. Please wait approximately 20 to 30 minutes for the anesthesia to take effect.
Administration or Delivery In the case of injection, culture supernatant is injected across the entire face or to areas of concern. In the case of delivery, culture supernatant is penetrated using a device. Treatment time is approximately 30 to 50 minutes.
Calming and Skincare After the procedure, we condition the skin with a calming pack or cream. If there are no problems, you may apply makeup before leaving.
Treatment Frequency and Intervals
To maximize the effects of stem cell culture supernatant dermal administration, appropriate treatment frequency and intervals are important.
Initial Treatment Period
Considering skin turnover, accumulating multiple treatments is recommended. During the first 2 to 3 months, we recommend receiving treatment at intervals of once every two weeks to once monthly. During this period, skin cell activation is promoted and skin quality improvement is pursued.
Maintenance Period
After completing the initial treatment period, we recommend continuing maintenance treatment at intervals of once every 1 to 2 months. Through regular treatment, youthful skin can be maintained. The optimal treatment plan differs depending on the patient’s skin condition and perception of effects.
Downtime and Precautions
While stem cell culture supernatant dermal administration is treatment with relatively minimal downtime, precautions differ depending on administration method.
Symptoms That May Occur After Treatment
In the case of injection, mild redness, swelling, or bruising may occur at sites where the needle was inserted; however, these naturally disappear within several days. In the case of delivery, there is virtually no downtime; however, the skin may become sensitive.
Precautions on Treatment Day
On the treatment day, we recommend avoiding strenuous exercise, prolonged bathing, and saunas. In the case of injection, makeup is possible on the same day; however, please be careful not to rub strongly. Face washing is possible as usual from the following day.
Those Who Cannot Receive Treatment
Pregnant women, nursing mothers, those with inflammation or infection on the skin, those with keloid-prone constitution, and those with a history of malignant tumors may not be able to receive treatment. During consultation, we will conduct detailed inquiries and determine whether treatment can be received safely.
Combination with Other Treatments
Stem cell culture supernatant dermal administration can be expected to produce synergistic effects when combined with other aesthetic treatments.
Combination with Infusion Therapy
Suppressing expression lines with botulinum toxin, supplementing volume with hyaluronic acid, and improving skin quality with stem cell culture supernatant—by combining these, more comprehensive rejuvenation is expected.
Combination with Laser Treatment
Conditioning the skin surface with laser treatment and regenerating the skin from the dermal layer with stem cell culture supernatant—through synergistic effects, higher skin beautification effects are expected.
Combination with External Products
Treatment effects can be further enhanced by using serums and creams containing culture supernatant as home care in combination.
Treatment Areas
Our clinic accommodates stem cell culture supernatant administration to the following areas:
Entire Face
We address rejuvenation of the entire face including the forehead, eye area, cheeks, mouth area, and chin.
Neck
We address improvement of neck wrinkles, sagging, and dullness.
Dorsal Hands
We address improvement of visible blood vessels, wrinkles, and dullness on the dorsal hands.
Other Areas
Please consult regarding other areas including the décolletage and arms.
Regarding Fees
Fees for stem cell culture supernatant dermal administration are as follows:
| Treatment | Fee |
|---|---|
| Entire Face (1 session) | ¥110,000–¥165,000 |
| Entire Face (3-session course) | ¥297,000–¥445,500 |
| Neck (1 session) | ¥88,000–¥132,000 |
| Dorsal Hands (1 session) | ¥88,000–¥132,000 |
| Face + Neck (1 session) | ¥165,000–¥247,500 |
*All prices are inclusive of tax. *Fees vary depending on administration method (injection or delivery) and dosage. Details will be explained during consultation.
Initial consultation and counseling fees are free. Payment is accepted via cash, credit cards, debit cards, and medical loans.
Frequently Asked Questions
We respond to questions commonly received from patients regarding stem cell culture supernatant dermal administration.
Is the injection painful?
Because we use anesthetic cream and perform the procedure with ultrafine needles, pain is minimized. In the case of the delivery method, needles are not used, so there is virtually no pain.
When can I expect to perceive effects?
Individual variation exists; however, many individuals perceive improved skin firmness and luster after 2 to 3 treatments. By accumulating multiple treatments, you can perceive effects more fully.
What is the difference from hyaluronic acid injection?
While hyaluronic acid injection physically plumps the skin, stem cell culture supernatant enhances the skin’s regenerative capacity itself. This is treatment that can be expected to achieve more natural and sustained effects.
Is there downtime?
In the case of injection, mild redness or bruising may remain for several days; however, this is to a degree that can be covered with makeup. In the case of delivery, there is virtually no downtime.
Is insurance coverage applicable?
Stem cell culture supernatant dermal administration is elective medical care; therefore, health insurance is not applicable.
Skin Regenerative Medicine Received in Ginza
AVAN TOKYO provides skin regenerative medicine in Ginza. Stem cell culture supernatant dermal administration represents a new option for those wishing to fundamentally improve skin quality and those seeking natural rejuvenation.
Recovering beautiful skin—this leads to recovering confidence. Finding it enjoyable to look in the mirror, finding makeup time delightful, no longer finding it painful to be photographed. Please recover radiant skin through stem cell culture supernatant dermal administration.
We conduct consultations free of charge, so please feel free to consult with us first. We will propose treatment plans tailored to each individual patient’s skin condition and provide maximum support toward realizing your ideal skin.