Stem Cell Culture Supernatant “Hair Growth Injection” for Thinning Hair and Hair Loss
Treatment Establishing the Regenerative Environment for Hair Follicles Themselves

AVAN TOKYO’s stem cell culture supernatant scalp injection is treatment that aims to activate hair matrix cells, improve blood flow around hair follicles, and maintain anagen-phase hair by directly injecting culture supernatant into the scalp. We provide cutting-edge regenerative medicine for hair loss in Ginza.
The primary characteristic of this treatment is that, unlike pharmacological therapy, it establishes a regenerative environment for the hair follicles themselves. This treatment is suitable for those concerned about medication side effects, individuals wishing to initiate early hair loss prevention measures, and those aiming for natural hair regrowth.
What Is Stem Cell Culture Supernatant Scalp Injection?

Stem cell culture supernatant scalp injection is treatment in which supernatant obtained during the process of culturing adipose-derived stem cells is directly injected into the scalp. This supernatant contains abundant growth factors, cytokines, exosomes, and other bioactive substances, and activation of hair matrix cells and improvement of the scalp environment are expected.
While conventional hair loss treatment medications have primarily aimed at suppressing hair loss, stem cell culture supernatant scalp injection aims to establish a regenerative environment for hair follicles. This is treatment expected to promote hair growth through a mechanism different from pharmaceutical agents such as finasteride and minoxidil.
Through direct administration to the scalp, direct action upon hair matrix cells is possible. Hair loss improvement is expected by improving blood flow around hair follicles, promoting hair matrix cell division, and maintaining anagen-phase hair.
Expected Effects
The following effects are expected from stem cell culture supernatant scalp injection:
Activation of Hair Matrix Cells
Through the action of growth factors, hair matrix cell division is promoted and hair growth becomes more active. Hair growth is promoted by transitioning hair follicles in the resting phase to the growth phase.
Improvement of Blood Flow Around Hair Follicles
When scalp blood flow improves, adequate nutrition and oxygen are supplied to hair roots. Blood flow improvement is an essential element for healthy hair growth.
Maintenance of Anagen-Phase Hair
In the hair growth cycle, thick and long hair develops by maintaining the growth phase for extended periods. Extension of the growth phase is expected through the action of stem cell culture supernatant.
Enhancement of Hair Thickness and Density
Through hair matrix cell activation, thinning hair becomes thicker and hair density increases. This leads to visible volume enhancement.
Improvement of Scalp Environment
By suppressing scalp inflammation and establishing a healthy scalp environment, soil conducive to hair growth is created. Scalp environment improvement is important for long-term hair loss prevention measures.
Recommended for Those Who:

Stem cell culture supernatant scalp injection is suitable for individuals with the following concerns:
Those who feel that hair loss has increased recently and hair volume has decreased. This is suitable for those wishing to initiate hair loss prevention measures at an early stage.
Those concerned about side effects of hair loss treatment medications. This is suitable for those wishing to avoid side effects such as sexual function decline from finasteride and those resistant to continuing medication.
Those using hair loss treatment medications but experiencing insufficient effects. This is suitable for those wishing to enhance effects in addition to current treatment.
Those suffering from female pattern hair loss or diffuse alopecia. This addresses hair loss from hormonal balance disruption and aging.
Those aiming for natural hair regrowth. This is suitable for those wishing to gradually increase hair in a natural manner rather than through unnatural rapid changes.
Our Clinic’s Commitment

At AVAN TOKYO, we provide stem cell culture supernatant scalp injection treatment with the following commitments:
Use of High-Quality Culture Supernatant
The stem cell culture supernatant used at our clinic is manufactured under rigorous quality control. We adopt only high-quality products that meet all standards including growth factor and exosome content and safety. Because this is the delicate treatment of hair growth, we are particular about quality.
Injection Technique Minimizing Pain
While scalp injection is a procedure accompanied by pain, our clinic implements measures to minimize pain. Through use of ultrafine needles, application of anesthetic cream, and careful technique, we reduce patient burden.
Administration Plan Tailored to Scalp Condition
We comprehensively evaluate the patient’s degree of hair loss progression, scalp condition, treatment objectives, and other factors to propose optimal dosage and administration sites. Rather than standardized treatment, we formulate treatment plans tailored to each individual.
Continuous Follow-Up and Effect Measurement
After treatment, we periodically confirm progress and record hair condition through photography and other means. We objectively evaluate effects and adjust treatment plans as necessary.
Treatment Process
Stem cell culture supernatant scalp injection treatment proceeds according to the following process:
Consultation
We conduct detailed inquiries regarding the patient’s hair loss condition, onset timing, family history, treatment history to date, and other relevant factors. We examine scalp condition and confirm the degree of hair loss progression. We provide detailed explanations regarding the mechanism of stem cell culture supernatant scalp injection, expected effects, risks and side effects, costs, and other matters.
Scalp Photography (Initial Visit)
To record the pre-treatment state, we photograph the scalp. This serves as material for objectively evaluating post-treatment effects.
Treatment Day
Scalp Cleansing and Disinfection We cleanse and disinfect the scalp thoroughly. Performing the procedure in a clean state is important.
Anesthesia (As Needed) To reduce pain, we apply anesthetic cream as necessary. Please wait approximately 15 to 20 minutes for the anesthesia to take effect.
Injection into Scalp We inject culture supernatant across the entire scalp, centered on areas where hair loss is of concern. Injection requires approximately 30 to 40 minutes. We use ultrafine needles and inject carefully while minimizing pain.Post-Treatment Care After injection, we lightly massage the scalp to facilitate culture supernatant penetration. If there are no problems, you may return home immediately.
Treatment Frequency and Intervals
To maximize the effects of stem cell culture supernatant scalp injection, appropriate treatment frequency and intervals are important.
Initial Treatment Period
Considering the hair growth cycle, accumulating multiple treatments is recommended. During the first 2 to 3 months, we recommend receiving treatment at intervals of once every two weeks to once monthly. During this period, hair matrix cell activation is promoted and the hair growth environment is established.
Maintenance Period
After completing the initial treatment period, we recommend continuing maintenance treatment at intervals of once every 1 to 2 months. Through regular treatment, the improved state can be maintained. The optimal treatment plan differs depending on the patient’s hair loss condition and perception of effects.
Downtime and Precautions
While stem cell culture supernatant scalp injection is treatment with relatively minimal downtime, several precautions exist.
Symptoms That May Occur After Treatment
Mild redness or swelling may occur at injection sites; however, these naturally disappear within several hours to several days. Rarely, mild headache or malaise may be experienced after injection; however, these are temporary and improve within several days.
Precautions on Treatment Day
On the treatment day, we recommend avoiding strenuous exercise, prolonged bathing, and saunas. Shampooing is possible from the following day; however, please wash gently without strongly rubbing the scalp. Please avoid wetting the scalp for 6 hours after treatment.
Those Who Cannot Receive Treatment
Pregnant women, nursing mothers, those with inflammation or infection on the scalp, and those with a history of malignant tumors may not be able to receive treatment. During consultation, we will conduct detailed inquiries and determine whether treatment can be received safely.
Combination with Other Treatments
Stem cell culture supernatant scalp injection can be expected to produce synergistic effects when combined with other treatments.
Combination with Infusion Therapy
By combining systemic infusion with local scalp injection, systemic blood flow improvement and localized hair matrix cell activation can be promoted simultaneously. More effective hair growth treatment is expected.
Combination with Hair Loss Treatment Medications
Combination with hair loss treatment medications such as finasteride and minoxidil is also possible. Higher effects are expected by combining hair loss suppression through pharmaceutical agents with hair growth promotion through stem cell culture supernatant.
Combination with External Products
Treatment effects can be further enhanced by using hair growth products and scalp serums containing culture supernatant as home care in combination.
Male Pattern Baldness (AGA) and Female Hair Loss

Our clinic accommodates both male pattern baldness (AGA) and female hair loss.
Male Pattern Baldness (AGA)
Hair loss in the frontal and crown areas is characteristic. Onset occurs due to genetic factors and hormonal influences. Hair matrix cell activation and hair follicle regeneration are expected through stem cell culture supernatant scalp injection.
Female Diffuse Alopecia
Thinning of hair across the entire head is characteristic. Hormonal balance disruption, stress, aging, and other factors serve as causes. Scalp environment improvement and hair growth promotion are expected through stem cell culture supernatant scalp injection.
Regarding Fees
Fees for stem cell culture supernatant scalp injection are as follows:
| Treatment | Fee |
|---|---|
| Scalp Injection (1 session) | ¥88,000–¥132,000 |
| Scalp Injection (3-session course) | ¥237,600–¥356,400 |
| Scalp Injection (6-session course) | ¥422,400–¥633,600 |
*All prices are inclusive of tax. *Fees vary depending on administration area and dosage. Details will be explained during consultation.
Initial consultation and counseling fees are free. Payment is accepted via cash, credit cards, debit cards, and medical loans.
Frequently Asked Questions
We respond to questions commonly received from patients regarding stem cell culture supernatant scalp injection.
Is the injection painful?
Scalp injection is accompanied by some pain; however, we reduce pain through use of anesthetic cream. We use ultrafine needles and employ careful technique, so please be assured.
When can I expect to perceive effects?
Individual variation exists; however, many individuals perceive reduced hair loss and hair volume enhancement in approximately 3 to 6 months. Considering the hair growth cycle, perception of effects requires time.
Is combination with hair loss treatment medications possible?
Yes, it is possible. Higher effects are expected through combination with pharmaceutical agents such as finasteride and minoxidil. If you are currently taking medications, please inform us during consultation.
Can women receive this treatment?
Yes, women can receive this treatment. Effects are also expected for female diffuse alopecia.
Is insurance coverage applicable?
Stem cell culture supernatant scalp injection is elective medical care; therefore, health insurance is not applicable.
Regenerative Medicine for Hair Loss Received in Ginza
AVAN TOKYO provides cutting-edge regenerative medicine for hair loss in Ginza. Stem cell culture supernatant scalp injection represents a new option for those wishing to avoid medication side effects and those aiming for natural hair regrowth.
Recovering abundant hair—this leads to recovering confidence. Not needing to worry about hats in public, no longer finding it painful to be photographed, finding it enjoyable to look in the mirror. Please recover confident everyday life through stem cell culture supernatant scalp injection.
We conduct consultations free of charge, so please feel free to consult with us first. We will propose treatment plans tailored to each individual patient’s hair loss condition and provide maximum support toward recovering your ideal hair.