Culture Supernatant-Containing Products for Home Care
Skincare Products Containing Culture Supernatant for Daily Home Care

At AVAN TOKYO, we offer serums and creams containing stem cell culture supernatant for home care.
Topical products can be used as part of your daily skincare at home, alongside treatment at the clinic.
What Are Culture Supernatant-Containing Products?

Products containing stem cell culture supernatant are skincare products, such as serums and creams, that contain supernatant obtained while culturing adipose-derived stem cells. The supernatant contains cytokines, exosomes and other components.
They are products for moisturizing and conditioning the skin as part of daily skincare. They contain the same type of culture supernatant used in the clinic’s injection and delivery treatments.
How products feel and how the skin changes vary from person to person.
What the Products Are For

As part of daily skincare, the products are intended for the following.
Moisturizing
They moisturize the skin and help prevent dryness.
Conditioning the skin
They smooth the skin texture and keep the skin healthy.
Firmness and radiance
Through moisturizing, they give the skin firmness and radiance.
Protecting the skin
They help protect the skin from dryness and the external environment.
After clinic treatment
After treatment at the clinic, they can be used as your daily skincare at home.
About how they feel
How products feel and how the skin changes vary from person to person. If a product does not suit your skin, stop using it and consult us.
Recommended for Those Who:

Culture supernatant-containing products are suitable for individuals with the following concerns:
People who want to continue skincare at home after treatment at the clinic.
People who want to make the most of home care while keeping clinic visits to a minimum.
People who are hesitant about injections or delivery treatments and want to start with skincare products.
People who want to review their daily skincare.
People who have started to notice dryness or loss of firmness with age.
Those with sensitive skin for whom ordinary cosmetics are unsuitable. This is suitable for those seeking low-irritation, skin-friendly products.
About Our Products

At AVAN TOKYO, we recommend products with the following in mind.
Quality-controlled culture supernatant
The stem cell culture supernatant in the products is manufactured under quality control, the same as that used for treatment at the clinic.
Skin-Friendly Formulation
The formula keeps ingredients that may irritate the skin, such as preservatives and fragrances, to a minimum. We recommend a patch test when using a product for the first time.
Formulated to blend into the skin
The formula is designed to blend easily into the skin.
Usage Method Advice
We explain how to use the products correctly, including the amount, timing and how to combine them with other cosmetics.
Product Lineup

Our clinic handles the following culture supernatant-containing products:
Culture Supernatant-Containing Serum
This is a serum formulated with high-concentration culture supernatant. Use after toner and before cream. It is characterized by a texture that absorbs smoothly into the skin without stickiness. It can be used for morning and evening skincare.
Several options are available depending on concentration and size. For first-time users, we recommend the standard concentration.
Culture Supernatant-Containing Cream
This is a moisturizing cream formulated with culture supernatant. Use after serum to seal active ingredients into the skin. With a moist texture, it is suitable for those concerned about dryness.
Morning and evening versions are available, each formulated for respective usage scenarios. The morning version has a smooth texture easy to use before makeup; the evening version has a rich texture that provides thorough moisturization.
Culture Supernatant-Containing Eye Cream
A culture supernatant-containing cream made especially for the eye area. It moisturizes the delicate skin around the eyes. A small amount spreads well and does not feel sticky.
Culture Supernatant-Containing Mask
This is a sheet mask formulated with high-concentration culture supernatant. It can be used for special care once or twice weekly. Use for 10 to 15 minutes imparts firmness and luster to the skin.
Usage Method
We explain basic usage methods for culture supernatant-containing products.
Morning Skincare
After face washing, condition skin with toner. Gently blend culture supernatant-containing serum across entire face. Thinly spread culture supernatant-containing cream (morning version) across entire face. Apply sunscreen or makeup as needed.
Evening Skincare
Thoroughly remove makeup and dirt with cleansing and face washing. Condition skin with toner. Gently blend culture supernatant-containing serum across entire face. Thoroughly blend culture supernatant-containing cream (evening version) across entire face. Use eye cream for the eye area.
Special Care
Use culture supernatant-containing mask once or twice weekly. After face washing, after conditioning skin with toner, adhere mask closely to face. After 10 to 15 minutes, remove mask and blend remaining serum into skin. Afterward, use cream as usual.
Storage Method and Expiration Date
Please store culture supernatant-containing products according to the following method:
Storage Method
Avoid direct sunlight and store in a cool location. After opening, refrigerator storage is recommended. To maintain cleanliness, always close the lid securely after use.
Expiration Date
If unopened, products can be used until the date indicated on the product. After opening, please use within 2 to 3 months. Because culture supernatant contains delicate components, we recommend using as quickly as possible after opening.
Combination with Other Treatments
Topical products can be used as daily skincare alongside treatment at the clinic.
Combination with Dermal Administration
You can receive skin injections or delivery treatment at the clinic and continue skincare at home with culture supernatant-containing products.
Combination with Infusion Therapy
People receiving infusion can also use topical products as part of daily skincare.
Combination with Other Aesthetic Treatments
Whether the products can be used after botulinum toxin, hyaluronic acid or laser treatment depends on the procedure. Please consult the doctor.
Regarding Fees
Fees for culture supernatant-containing products are as follows:
| Product | Fee |
|---|---|
| Culture Supernatant-Containing Serum (1 month supply) | ¥33,000–¥55,000 |
| Culture Supernatant-Containing Cream (1 month supply) | ¥44,000–¥66,000 |
| Culture Supernatant-Containing Eye Cream (1 month supply) | ¥22,000–¥33,000 |
| Culture Supernatant-Containing Mask (5 sheets) | ¥16,500–¥22,000 |
*All prices are inclusive of tax. *Fees vary depending on product type and concentration. Details will be explained during consultation.
Initial consultation and counseling fees are free. Payment is accepted via cash, credit cards, debit cards, and medical loans.
Frequently Asked Questions
We respond to questions commonly received from patients regarding culture supernatant-containing products.
What is the difference from ordinary cosmetics?
Like ordinary cosmetics, they are skincare products for moisturizing and conditioning the skin. Their distinguishing feature is that they contain stem cell culture supernatant.
Can those with sensitive skin use these products?
Yes. The formula keeps ingredients that may irritate the skin to a minimum, but we recommend a patch test the first time. If a product does not suit your skin, stop using it.
When can I expect to perceive effects?
How products feel and how the skin changes vary from person to person.
Can these be used in combination with other cosmetics?
Yes, they can be used in combination. After toner, use culture supernatant-containing serum, followed by cream, sunscreen, and other cosmetics you ordinarily use.
How long should these be used?
They can be used continuously as daily skincare. Please consult us about how long to use them according to your skin condition.
Home-Care Products Containing Culture Supernatant Available in Ginza
AVAN TOKYO Ginza carries skincare products containing culture supernatant. The first purchase is made after a consultation.
The products are easy to include in your daily skincare. Please feel free to ask us how to use and combine them.
Consultations are free. We suggest products suited to your skin condition.