Intranasal Administration Approaching the Entire Body Through Nasal Mucosa
Easily Accessible Regenerative Medicine
AVAN TOKYO’s stem cell culture supernatant intranasal administration is treatment that offers expectations of benefits to the brain and nervous system and systemic effects by allowing direct absorption of culture supernatant through nasal mucosa. We provide the most easily accessible regenerative medicine in Ginza.
This is a suitable method for those uncomfortable with injections or those wishing to incorporate regenerative medicine more conveniently. Because nasal mucosa is rich in blood vessels with high absorption rates, systemic effects comparable to infusion are expected. Additionally, because this represents administration from a site proximate to the brain, effects on the nervous system are also attracting attention.
What Is Stem Cell Culture Supernatant Intranasal Administration?
Stem cell culture supernatant intranasal administration is treatment in which supernatant obtained during the process of culturing adipose-derived stem cells is sprayed into the nasal cavity like a nasal medication. This supernatant contains abundant growth factors, cytokines, exosomes, and other bioactive substances, and is directly absorbed through nasal mucosa.
Nasal mucosa is a site extremely rich in blood vessels with high substance absorption rates. Therefore, through intranasal administration, components of culture supernatant are rapidly incorporated into the bloodstream and transported throughout the body. Additionally, because the nose is a site proximate to the brain, direct benefits to the brain and nervous system are also expected.
While conventional infusion treatment involved administration from veins, intranasal administration utilizes the new route of absorption through nasal mucosa. Because injection needles are not used, this is a treatment method without pain and with minimal psychological burden.
Expected Effects
The following effects are expected from stem cell culture supernatant intranasal administration:
Fatigue Reduction
Through activation of cells throughout the body, reduction of chronic fatigue is expected. Daily fatigue accumulates less readily, and recovery of a vital everyday life is expected.
Sleep Quality Improvement
Through regulation of autonomic nervous system balance, sleep quality improvement is expected. Changes are expected such as improved ability to fall asleep, deeper sleep, and ability to wake refreshed in the morning.
Concentration Improvement
Through improved blood flow to the brain, enhancement of concentration and memory is expected. Improvement of work and study performance is expected.
Stress Tolerance Enhancement
Through effects on the nervous system, enhancement of stress tolerance is expected. Mental stability is obtained, and reduced irritability is expected.
Immune Function Regulation
As a systemic effect, regulation of immune function balance is expected. Benefits are expected such as reduced susceptibility to colds and alleviation of allergy symptoms.
Cognitive Function Support
Through administration from a site proximate to the brain, cognitive function support is expected. These are effects that can be expected for those concerned about forgetfulness and those feeling that mental acuity has declined.
Recommended for Those Who:
Stem cell culture supernatant intranasal administration is suitable for individuals with the following concerns:
Those uncomfortable with injections and resistant to infusion treatment. This is suitable for those wishing to receive regenerative medicine through a painless method.
Those wishing to conveniently incorporate regenerative medicine into daily life. This is suitable for busy individuals and those for whom regular clinic visits are difficult.
Those experiencing persistent fatigue and malaise. This is suitable for those experiencing chronic fatigue such as fatigue that does not dissipate despite sleep and difficulty waking in the morning.
Those with poor sleep quality. This is suitable for those with sleep concerns such as difficulty falling asleep, waking multiple times during the night, and inability to wake refreshed in the morning.
Those experiencing declined concentration and memory. This is suitable for those feeling that work and study efficiency has declined and forgetfulness has increased.
Those experiencing significant stress and seeking mental stability. This is suitable for those who are easily irritated and experience severe mood fluctuations.
Our Clinic’s Commitment
At AVAN TOKYO, we provide stem cell culture supernatant intranasal administration treatment with the following commitments:
Use of High-Quality Culture Supernatant
The stem cell culture supernatant used at our clinic is manufactured under rigorous quality control. We adopt only high-quality products that meet all standards including growth factor and exosome content and safety. Because this is absorbed through nasal mucosa, we are particular about quality.
Setting of Appropriate Dosage
We propose optimal dosage considering the patient’s body weight, age, symptoms, and other factors. While intranasal administration is a treatment method that can be continued at home, adhering to the appropriate amount is important.
Instruction in Proper Usage Method
While intranasal administration is a simple method, maximum effects can be drawn out by adhering to proper usage methods. We provide careful instruction regarding usage methods.
Continuous Follow-Up
We periodically confirm progress and verify perception of effects and changes in physical condition. We adjust dosage and frequency as necessary.
Treatment Process
Stem cell culture supernatant intranasal administration treatment proceeds according to the following process:
Consultation
We conduct detailed inquiries regarding the patient’s current health status, concerns, treatment objectives, and other relevant factors. We also confirm presence or absence of allergies and nasal diseases. We provide detailed explanations regarding the mechanism of stem cell culture supernatant intranasal administration, expected effects, risks and side effects, costs, and other matters.
Initial Administration and Usage Method Instruction
Initially, intranasal administration is performed in the clinic and proper usage methods are instructed. We provide detailed explanations regarding nasal spray usage, administration timing, storage methods, and other matters.
Continued Use at Home
Please take the nasal spray home and use it continuously at your residence. Please use once or twice daily, or according to physician instructions.
Regular Follow-Up
Please visit approximately once every 1 to 2 months for effect confirmation and prescription of additional nasal spray. We adjust dosage and frequency as necessary.
Usage Method
Stem cell culture supernatant intranasal administration is performed according to the following procedure:
Preparation Before Administration
Blow your nose to cleanse the nasal cavity. Shake the nasal spray lightly and perform 1 to 2 blank sprays with the nozzle pointed upward.
Administration
Tilt your head slightly forward and insert the nozzle into the nasal cavity. Press the opposite nostril closed with your finger, and inhale lightly while spraying. Administer similarly to the other nostril.
After Administration
After administration, maintain the head-tilted-forward position for several minutes to prevent liquid from flowing out of the nose. Please do not blow your nose.
Storage Method
Please store the nasal spray in the refrigerator. It is important to avoid direct sunlight and maintain clean storage.
Usage Frequency and Duration
To maximize the effects of stem cell culture supernatant intranasal administration, appropriate usage frequency and duration are important.
Initial Usage Period
During the first 1 to 2 months, we recommend usage once or twice daily. During this period, you perceive effects and experience bodily changes.
Maintenance Period
After perceiving effects, we recommend continuing usage once daily. Through regular usage, the improved state can be maintained. The optimal usage frequency differs depending on patient condition and perception of effects.
Precautions
While stem cell culture supernatant intranasal administration is a highly safe treatment, several precautions exist.
Symptoms That May Occur After Use
Mild irritation or discomfort may be felt within the nasal cavity; however, this is temporary and disappears within minutes. Rarely, mild sneezing or nasal discharge may occur; however, this is not a concern.
Usage Precautions
If inflammation or infection exists in the nose, please refrain from use. When you have a cold or when nosebleeds are occurring, please do not use. When allergic rhinitis symptoms are severe, please consult with a physician.
Those Who Cannot Use
Pregnant women, nursing mothers, those with severe nasal diseases, and those with a history of malignant tumors may not be able to use this treatment. During consultation, we will conduct detailed inquiries and determine whether safe usage is possible.
Combination with Other Treatments
Stem cell culture supernatant intranasal administration can be expected to produce synergistic effects when combined with other treatments.
Combination with Infusion Therapy
By combining systemic administration via infusion with intranasal administration, more effective comprehensive rejuvenation is expected. Two approaches are possible: infusion for the entire body and intranasal for the brain and nervous system.
Combination with Other Local Administrations
By combining with scalp injection or dermal administration, treatment from both systemic and local perspectives is possible. The combination of local administration to areas of concern and intranasal administration for systemic care is effective.
Combination with External Products
Treatment effects can be further enhanced by using external products containing culture supernatant as home care in combination.
Regarding Fees
Fees for stem cell culture supernatant intranasal administration are as follows:
| Treatment | Fee |
|---|---|
| Intranasal Administration (1 session, approximately 1 month supply) | ¥55,000–¥88,000 |
| Intranasal Administration (5-session course) | ¥220,000–¥352,000 |
*All prices are inclusive of tax. *Fees vary depending on dosage. Details will be explained during consultation.
Initial consultation and counseling fees are free. Payment is accepted via cash, credit cards, debit cards, and medical loans.
Frequently Asked Questions
We respond to questions commonly received from patients regarding stem cell culture supernatant intranasal administration.
Is intranasal administration painful?
There is no pain whatsoever. Just like nasal medication, it merely involves spraying into the nose. Mild irritation may be felt; however, you quickly become accustomed.
When can I expect to perceive effects?
Individual variation exists; however, many individuals perceive fatigue reduction and sleep quality improvement in approximately 1 to 2 weeks. By using continuously, you can perceive effects more fully.
How many times daily should I use it?
Basically, we recommend usage once or twice daily. We propose morning and evening, or morning only, according to the patient’s lifestyle.
What is the difference from infusion?
While infusion administers systemically from veins, intranasal is absorbed through nasal mucosa. Intranasal has the advantages of no pain and ability to continue at home. Additionally, because it represents administration from a site proximate to the brain, effects on the nervous system are expected.
Is insurance coverage applicable?
Stem cell culture supernatant intranasal administration is elective medical care; therefore, health insurance is not applicable.
Convenient Regenerative Medicine Received in Ginza
AVAN TOKYO provides the most easily accessible regenerative medicine in Ginza. Stem cell culture supernatant intranasal administration represents a new option for those uncomfortable with injections, busy individuals, and those wishing to conveniently incorporate regenerative medicine.
Reducing daily fatigue and recovering high-quality sleep—this leads to enhancing quality of life. Waking refreshed in the morning, enhanced daytime performance, increased stress resilience. Please recover a vital everyday life through stem cell culture supernatant intranasal administration.
We conduct consultations free of charge, so please feel free to consult with us first. We will propose usage methods tailored to each individual patient’s condition and provide maximum support toward realizing your ideal health status.