“Intranasal Administration” of Stem Cell Culture Supernatant
Intranasal Administration of Stem Cell Culture Supernatant, Without Injection
Intranasal administration of stem cell culture supernatant at AVAN TOKYO is a method in which the culture supernatant is sprayed into the nasal cavity, like a nasal spray. Because no needle is used, it can also be considered by people who dislike injections.
Our main treatment is scalp injection for thinning hair; intranasal administration is offered as one of our other methods. What can be expected and whether it is suitable are explained at the examination after we hear your goals.
What Is Intranasal Administration of Stem Cell Culture Supernatant?
The supernatant obtained while culturing adipose-derived stem cells is sprayed into the nasal cavity. It contains cytokines, exosomes and other components. The cells themselves are not administered.
This method relies on absorption through the nasal mucosa, a different route from infusion (intravenous administration). Any changes you notice vary from person to person, and results are not guaranteed. This is elective (self-pay) treatment, so health insurance does not apply.
Who Consults Us
- People who are reluctant to have injections or infusions
- People who want to keep clinic visits to a minimum
- People who want to consider it together with other methods
How We Proceed
Quality-controlled culture supernatant
The stem cell culture supernatant we use is manufactured under quality control.
Setting the dose
We suggest a dose taking into account your age, weight, health and goals.
Explaining how to use it
At the first visit, we show you in the clinic how to use the spray correctly.
Follow-up
We check your progress regularly and adjust the dose or frequency as needed.
Treatment Process
Consultation and examination
We ask about your current health, goals, allergies and any nasal conditions, and explain the treatment, its risks and side effects, and the fees.
First dose and instructions
The first dose is given in the clinic, and we explain how to use the spray, when to use it and how to store it.
Use at home
You take the nasal spray home and use it once or twice a day, or as directed by the doctor.
Regular visits
You visit about once every 1 to 2 months so we can check your progress and prescribe more spray.
How to Use
Before use
Blow your nose to clear the nasal cavity. Shake the spray gently and prime it once or twice with the nozzle pointing up.
Using the spray
Tilt your head slightly forward and place the nozzle in one nostril. Press the other nostril closed with a finger and spray while breathing in gently. Repeat on the other side.
After use
Keep your head tilted forward for a few minutes and avoid blowing your nose.
Storage
Store in the refrigerator, away from direct sunlight, and keep it clean.
How Often to Use
As a guide, once or twice a day for the first 1 to 2 months, then once a day depending on your condition. The best frequency differs with your condition and goals.
Precautions
Possible symptoms after use
Mild irritation or discomfort in the nose may occur and usually disappears within a few minutes. Occasionally, sneezing or a runny nose may occur.
When to avoid use
Do not use it when your nose is inflamed or infected, when you have a cold, or when you have a nosebleed. If allergic rhinitis symptoms are severe, please consult the doctor.
Who cannot use it
People who are pregnant or breastfeeding, have a serious nasal condition, or have a history of malignant tumors may not be able to use it. We will ask in detail at the consultation and decide.
Combining with Other Treatments
Infusion
If you wish, it can be combined with infusion.
Scalp injection
It can also be received alongside scalp injections for thinning hair.
Fees
| Treatment | Fee |
|---|---|
| Intranasal Administration (1 session) | ¥65,000–¥98,000 |
| Intranasal Administration (5-session course) | ¥240,000–¥372,000 |
The initial examination and consultation are free. We accept cash, credit cards, debit cards and medical loans.
Frequently Asked Questions
Is it painful?
No needle is used. You spray it into the nose like a nasal spray. You may feel mild irritation.
How many times a day do I use it?
Basically once or twice a day. We suggest a routine that fits your lifestyle.
How is it different from infusion?
Infusion is given into a vein, while intranasal administration is absorbed through the nasal mucosa. It uses no needle and can be continued at home.
When will I notice results?
How and when changes are noticed varies from person to person. Results are not guaranteed, so we explain your goals and what can be expected at the examination.
Is insurance coverage available?
No. This is elective (self-pay) treatment, so health insurance does not apply.
Intranasal Administration in Ginza
AVAN TOKYO Ginza is a 1-minute walk from Ginza-itchome Station. If you would prefer a method without injection, please consult us first.
Consultations are free and available in English, Chinese and Vietnamese.