Stem Cell Culture Supernatant “Joint Injection” for Osteoarthritis and Joint Pain
A New Option for Those Wishing to Avoid Surgery
AVAN TOKYO’s stem cell culture supernatant joint injection is treatment that aims to calm inflammation, promote repair of cartilage-surrounding tissues, and reduce pain by directly injecting culture supernatant into joints such as the knee and shoulder. We provide cutting-edge regenerative medicine for joint pain in Ginza.
We propose this as regenerative medicine targeting fundamental improvement for concerns such as difficulty with stair climbing, inability to sit in seiza position, and pain during ambulation. This option is gaining attention as a low-burden alternative for the body, particularly for those who have not experienced improvement with hyaluronic acid injections or wish to avoid surgical intervention when possible.
What Is Stem Cell Culture Supernatant Joint Injection?
Stem cell culture supernatant joint injection is treatment in which supernatant obtained during the process of culturing adipose-derived stem cells is directly injected into joints. This supernatant contains abundant growth factors, cytokines, exosomes, and other bioactive substances, and is expected to suppress inflammation within joints and promote tissue repair.
While conventional hyaluronic acid injections have aimed at joint lubrication, stem cell culture supernatant injection aims to establish a regenerative environment for the joints themselves. Rather than temporarily suppressing symptoms with analgesics or hyaluronic acid, this is treatment expected to fundamentally improve joint inflammation and promote tissue repair.
Particularly in osteoarthritis of the knee, improvement of symptoms is expected through growth factors that promote tissue repair acting upon inflammation and pain caused by cartilage wear. We believe patients should try regenerative medicine with minimal physical burden before the option of surgery.
Expected Effects
The following effects are expected from stem cell culture supernatant joint injection:
Calming of Inflammation
By suppressing chronic inflammation within joints, reduction of pain and swelling is expected. When inflammation is suppressed, joint movement also becomes smoother and quality of daily life improves.
Promotion of Cartilage-Surrounding Tissue Repair
Through the action of growth factors, promotion of tissue repair surrounding cartilage is expected. While complete regeneration of lost cartilage is difficult, improvement of joint function is expected by improving the surrounding tissue environment.
Pain Reduction
Through inflammation suppression and tissue repair, reduction of joint pain is expected. Liberation from a life dependent on analgesics and recovery of an active everyday life are expected.
Improvement of Joint Range of Motion
When pain and inflammation are reduced, improvement of joint range of motion is expected. Some individuals experience changes such as becoming able to sit in seiza position and finding stair climbing easier.
Suppression of Progression
By suppressing joint inflammation and improving the tissue environment, slowing the progression of osteoarthritis is expected. Through early treatment, the possibility of avoiding surgery also increases.
Recommended for Those Who:
Stem cell culture supernatant joint injection is suitable for individuals with the following concerns:
Those diagnosed with osteoarthritis of the knee who experience pain during stair climbing or ambulation. This is suitable for those experiencing interference with daily life such as inability to sit in seiza position and difficulty standing for extended periods.
Those receiving hyaluronic acid injections but experiencing insufficient effects. This is suitable for those obtaining only temporary improvement and seeking fundamental treatment.
Those recommended for surgery but wishing to avoid surgery if possible. This is suitable for those desiring treatment with minimal physical burden.
Those suffering from joint pain in the shoulder, elbow, ankle, or other areas. This is suitable for those wishing to improve joint pain from sports or work.
Those who wish to avoid reliance on analgesic medications. This is suitable for those concerned about medication side effects and those aiming for fundamental improvement.
Our Clinic’s Commitment
At AVAN TOKYO, we provide stem cell culture supernatant joint injection treatment with the following commitments:
Use of High-Quality Culture Supernatant
The stem cell culture supernatant used at our clinic is manufactured under rigorous quality control. We adopt only high-quality products that meet all standards including growth factor and exosome content and safety. Because this involves administration to the important site of joints, we are uncompromising regarding quality.
Careful Imaging Diagnosis and Treatment Planning
Prior to treatment, we perform imaging diagnostics such as X-rays or MRI as necessary to accurately assess joint condition. We comprehensively evaluate the degree of joint deformity, inflammation status, cartilage condition, and other factors to propose the optimal treatment plan for each patient.
Injection Technique Minimizing Pain
While joint injection is a procedure accompanied by pain, our clinic implements measures to minimize pain. Through use of fine needles, anesthesia of injection sites, and careful technique, we reduce patient burden.
Continuous Follow-Up After Treatment
After treatment, we periodically confirm progress and verify perception of effects and changes in pain. We adjust treatment plans as necessary and support optimal results.
Treatment Process
Stem cell culture supernatant joint injection treatment proceeds according to the following process:
Consultation
We conduct detailed inquiries regarding symptoms of the patient’s joint pain, onset timing, treatment history to date, and other relevant factors. We confirm interference with daily life, degree of pain, treatment objectives, and other matters. We provide detailed explanations regarding the mechanism of stem cell culture supernatant joint injection, expected effects, risks and side effects, costs, and other matters.
Imaging Diagnosis (As Needed)
To accurately assess joint condition, we perform imaging diagnostics such as X-rays or MRI as necessary. Based on imaging diagnosis results, we determine treatment appropriateness and treatment planning.
Treatment Day
Disinfection and Anesthesia We carefully disinfect the injection site. To reduce pain, we perform local anesthesia as necessary.
Injection into Joint Under ultrasound guidance or through palpation, we accurately inject culture supernatant into the joint. Injection requires approximately several minutes. We adjust dosage according to patient condition and joint size.
Rest After Treatment After injection, please rest in the clinic for approximately 10 to 15 minutes. We confirm joint condition, and if there are no problems, you may return home.
Treatment Frequency and Intervals
To maximize the effects of stem cell culture supernatant joint injection, appropriate treatment frequency and intervals are important.
Initial Treatment Period
In many cases, accumulating multiple treatments allows fuller perception of effects. During the first 1 to 2 months, we recommend receiving treatment at intervals of once every two weeks. During this period, inflammation suppression and tissue repair are promoted.
Maintenance Period
After completing the initial treatment period, we recommend continuing maintenance treatment at intervals of once every 1 to 2 months. Through regular treatment, the improved state can be maintained. The optimal treatment plan differs depending on the patient’s joint condition and symptoms.
Downtime and Precautions
While stem cell culture supernatant joint injection is treatment with relatively minimal downtime, because it involves injection into joints, several precautions exist.
Symptoms That May Occur After Treatment
Mild pain or swelling may occur at the injection site; however, these naturally diminish within several days. Rarely, pain may temporarily increase after injection; however, this is part of the inflammatory response and improves within several days.
Precautions on Treatment Day
On the treatment day, we recommend avoiding strenuous exercise and prolonged walking. Cooling the affected area can reduce swelling and pain. Showering is possible from the same day; however, we recommend long baths and saunas from the following day onward.
Those Who Cannot Receive Treatment
Pregnant women, nursing mothers, those with severe joint deformity, those with infection within joints, and those with a history of malignant tumors may not be able to receive treatment. During consultation, we will conduct detailed inquiries and determine whether treatment can be received safely.
Combination with Other Treatments
Stem cell culture supernatant joint injection can be expected to produce synergistic effects when combined with other treatments.
Combination with Infusion Therapy
By combining systemic infusion with local injection into joints, systemic anti-inflammatory effects and local tissue repair can be promoted simultaneously. More effective treatment is expected.
Combination with Rehabilitation
When appropriate rehabilitation is performed in a state where pain and inflammation have been reduced through joint injection, improvement of joint function is further promoted. We recommend incorporating exercise therapy within reasonable limits under the guidance of physical therapists.
Combination with Other Treatments
We will also propose combinations with other treatment methods according to patient condition. Please consult regarding the optimal treatment plan during your consultation appointment.
Joints That Can Be Treated
Our clinic accommodates stem cell culture supernatant injection to the following joints:
Knee Joint
We address osteoarthritis of the knee, knee pain and swelling, restriction of joint range of motion, and other conditions.
Shoulder Joint
We address frozen shoulder, shoulder pain and range of motion restriction, rotator cuff injury, and other conditions.
Elbow Joint
We address tennis elbow, golfer’s elbow, elbow pain, and other conditions.
Ankle Joint
We address ankle pain and swelling, chronic symptoms following sprains, and other conditions.
Other Joints
Please consult regarding other joints including the wrist and hip joint.
Regarding Fees
Fees for stem cell culture supernatant joint injection are as follows:
| Treatment | Fee |
|---|---|
| Knee Joint Injection (1 session) | ¥110,000–¥165,000 |
| Knee Joint Injection (3-session course) | ¥297,000–¥445,500 |
| Other Joints (shoulder, elbow, ankle, etc.) (1 session) | ¥88,000–¥132,000 |
*All prices are inclusive of tax. *Fees vary depending on joint condition and dosage. Details will be explained during consultation.
Initial consultation and counseling fees are free. Payment is accepted via cash, credit cards, debit cards, and medical loans.
Frequently Asked Questions
We respond to questions commonly received from patients regarding stem cell culture supernatant joint injection.
Is the injection painful?
Joint injection is accompanied by some pain; however, we reduce pain through use of local anesthesia. We use fine needles and employ careful technique, so please be assured.
When can I expect to perceive effects?
Individual variation exists; however, many individuals perceive pain reduction and improvement of joint movement after 2 to 3 treatments. By accumulating multiple treatments, you can perceive effects more fully.
What is the difference from hyaluronic acid injection?
While hyaluronic acid injection aims at joint lubrication, stem cell culture supernatant injection aims at tissue repair and inflammation suppression. This is treatment that can be expected to achieve more fundamental improvement.
Can surgery be avoided?
This depends on joint condition; however, through early treatment, the possibility of avoiding surgery exists. However, when severe deformity exists, surgery may become necessary.
Is insurance coverage applicable?
Stem cell culture supernatant joint injection is elective medical care; therefore, health insurance is not applicable.
Regenerative Medicine for Joint Pain Received in Ginza
AVAN TOKYO provides cutting-edge regenerative medicine for joint pain in Ginza. Stem cell culture supernatant joint injection represents a new option for those wishing to avoid surgery and those aiming for fundamental improvement.
Recovering a life without pain—this leads to enhancing quality of life. Climbing and descending stairs without concern, enjoying hobby sports, fully enjoying travel. Please recover an active everyday life through stem cell culture supernatant joint injection.
We conduct consultations free of charge, so please feel free to consult with us first. We will propose treatment plans tailored to each individual patient’s joint condition and provide maximum support toward realizing a life without pain.